Description
Details
Uses
Chlorambucil is used in combination to treat some types of blood cancers like Hodgkin's disease (cancer of lymphatic tissues typically causing painless enlargement of the lymph nodes, liver, and spleen), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (cancers of the lymph tissue that affects a type of white blood cell called B-lymphocytes). It is also used to treat Waldenstrom's macroglobulinemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood).
How it works
Chlorambucil belongs to a class of drugs called nitrogen mustard derivatives. It kills the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth.
Common side effects
diarrhea and oral ulcers., nausea, vomiting, Ineffective production of blood cells, low count of all or particular type of white blood cell, fits in children with nephrotic syndrome, anemia, decrease in all types of blood cells or bone marrow suppression, abnormally low platelet cells